PCNA Antikörper (C-Term)

Produktnummer ABIN7448997

Dieses Anti-PCNA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PCNA in IHC und IF (p). Geeignet für Human und Maus.

Kurzübersicht für PCNA Antikörper (C-Term) (ABIN7448997)

Target: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCNA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PCNA Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-PCNA IHC Antibody, Affinity Purified

Homologie: Rat,Sheep,Bovine,Dog,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Thirteen-lined ground squirrel,Northern white-cheeked gibbon,Crab-eating macaque,Small-eared galago,Little brown bat,Chinese hamster,Naked mole rat

Aufreinigung: Affinity Purified

Immunogen: Between AA 225 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PCNA

Target: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Andere Bezeichnung: PCNA

Hintergrund: Background: PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.

Gen-ID: 5111

NCBI Accession: NP_002583

UniProt: P12004

Pathways: Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagie